Hand Center Recent Publications

Source
The Journal of Shoulder and Elbow Surgery

Description
Repetitive stress injuries to the rotator cuff, and particularly the supraspinatus tendon (SST), are highly prevalent and debilitating. These injuries typically occur through the application of cyclic load below the threshold necessary to cause acute tears, leading to accumulation of incremental damage that exceeds the body's ability to heal, resulting in decreased mechanical strength and increased risk of frank rupture at lower loads. Consistent progression of fatigue damage across multiple...

Summary
Rotator cuff injuries, especially those involving the supraspinatus tendon (SST), are common and often result from repetitive stress rather than a single traumatic event. This review examines how cyclic loading below the level needed to cause an immediate tear can gradually accumulate damage in the SST, eventually overwhelming the body's natural repair processes and increasing the risk of full tendon rupture. The authors analyzed findings across multiple model systems and found a consistent pattern of fatigue damage progression, suggesting that tendons respond to overuse in a predictable, generalizable way. This consistency is significant because it raises the possibility of identifying early warning signs and developing interventions before serious injury occurs. The authors call for future research to better define the SST's fatigue life — including how much load, how often, and for how long it can be applied before injury — and to enable real-time strain analysis during everyday activities.

Publication Date
2022-08-05

Faculty
Nicholas Iannuzzi, MD

Source
The Journal of Shoulder and Elbow Surgery

Description
Overuse injuries of the rotator cuff, particularly of the supraspinatus tendon (SST), are highly prevalent and debilitating in work, sport, and daily activities. Despite the clinical significance of these injuries, there remains a large degree of uncertainty regarding the pathophysiology of injury, optimal methods of nonoperative and operative repair, and how to adequately assess tendon injury and healing. The tendon response to fatigue damage resulting from overuse is different from that of...

Summary
Rotator cuff injuries, especially those affecting the supraspinatus tendon (SST), are extremely common and can significantly limit a person's ability to work, exercise, or perform everyday tasks. This review examines how the SST responds to repetitive overuse injury, which differs from sudden tears and can lead to either healing or progressive degeneration depending on a range of biological and lifestyle factors. Key factors that increase the risk of degeneration include older age, smoking, high cholesterol, diabetes, and applying too much physical load to the tendon before it has recovered. On average, tendons heal at roughly 1% per day, a rate that can be slowed in females due to lower collagen production rates. While MRI remains the standard tool for diagnosing SST injuries, ultrasound imaging is emerging as a practical, real-time method for tracking structural and mechanical changes in the tendon, potentially helping clinicians identify activity levels that put patients at risk for complete rupture.

Publication Date
2022-07-08

Faculty
Nicholas Iannuzzi, MD

Source
Plastic and Reconstructive Surgery. Global Open

Description
CONCLUSIONS: Osteoplastic thumb reconstruction is a useful technique for thumb reconstruction for select patients following traumatic thumb amputation. Advantages of this approach include shorter overall operative times and hospital length of stay, minimal donor site morbidity, and a straightforward, reproducible technique.

Summary
Traumatic thumb amputation can severely impair hand function, and when reattachment of the amputated thumb is not possible, surgeons must find alternative ways to rebuild the thumb. This case series describes an immediate osteoplastic reconstruction technique, in which a bone graft and a pedicled groin flap—a section of skin and tissue from the patient's own hip area—are used to reconstruct the thumb right after injury, rather than waiting weeks or months. Five patients underwent this procedure between 2016 and 2018, with an average initial surgery time of about 158 minutes, and patients gained an average of 3.3 cm in thumb length compared to what a standard amputation revision would have provided. Patients required only about one additional minor procedure on average, such as tissue trimming or hardware removal, and all showed stable outcomes for at least one year. This approach is significant because it offers a simpler, faster, and more accessible alternative to complex microsurgical thumb reconstruction, with minimal complications at the donor site and consistent, reproducible results.

Publication Date
2022-06-20

Faculty
Yusha Katie Liu, MD
Erin Miller, MD

Source
Annals of Plastic Surgery

Description
CONCLUSIONS: Overall, patients with upper extremity NSTIs survive and undergo successful reconstruction of their wounds. Few patients required additional procedures for reconstructive failure or sequela of their wounds.

Summary
This study investigated how surgeons reconstruct the large wounds left behind after treating necrotizing soft tissue infections (NSTIs) — a severe, life-threatening bacterial infection that rapidly destroys skin and muscle — in the upper extremities. Researchers reviewed medical records of 99 patients treated at a single hospital between 2014 and 2019, analyzing wound sizes, number of surgical cleanings, reconstruction techniques, and complications. The average patient required about 3.4 debridement surgeries to remove infected tissue, and the resulting wounds were substantial, with a median size of 100 cm². Most surviving patients had their wounds successfully closed using relatively straightforward techniques such as delayed primary closure, skin grafting, or a combination of both, while a smaller number required more complex reconstructive flap procedures. The findings are significant because they demonstrate that, despite the severity of these infections — which resulted in amputation for 7 patients and death for 12 — the majority of patients achieved successful wound reconstruction with a low rate of major complications, providing useful guidance for surgical planning in this challenging patient population.

Publication Date
2022-06-15

Faculty
Stephen Kennedy, MD

Description
SUMMARY: In patients with severe upper extremity weakness that may result from peripheral nerve injuries, stroke, and spinal cord injuries, standard therapy in the earliest stages of recovery consists primarily of passive rather than active exercises. Adherence to prescribed therapy may be poor, which may contribute to suboptimal functional outcomes. The authors have developed and integrated a custom surface electromyography device with a video game to create an interactive, biofeedback-based...

Publication Date
2022-05-11

Faculty
Yusha Katie Liu, MD

Source
Plastic and Reconstructive Surgery

Description
CONCLUSIONS: Lack of a vein for anastomosis should not be regarded as a contraindication to replantation. These digits instead require a method to establish reliable drainage sufficient to allow for low resistance inflow and maintain a physiologic pressure gradient across capillary beds. The surgeon should select a decongestive technique that best suits the patient and their specific injury.

Summary
This study examined how surgeons manage finger reattachment (replantation) when only the artery can be repaired and no suitable vein is available to restore normal blood drainage. Researchers conducted a systematic review, analyzing 55 published articles that described 1,498 individual finger replantations where venous repair was not performed. Because blood cannot drain naturally without venous repair, various techniques to relieve congestion were evaluated, including medicinal leech therapy and surface bleeding methods, along with different anticoagulation strategies to prevent clotting. The overall survival rate for reattached fingers was 78.5%, though results varied considerably depending on the specific technique used and the study reviewed. The findings suggest that the inability to repair a vein should not automatically disqualify a patient from replantation, and that surgeons should choose the most appropriate drainage technique based on individual patient circumstances and injury type.

Publication Date
2022-05-10

Faculty
Erin Miller, MD

Source
The Journal of Hand Surgery

Description
CONCLUSIONS: Necrotizing soft tissue infection of the upper extremity carries risk of mortality and amputation, and effective treatment requires prompt recognition, early goal-directed resuscitation, and early debridement. The strongest independent predictor of in-hospital mortality was vasopressor dependence outside operative anesthesia. The LRINEC score did not strongly predict death or amputation in upper extremity NSTI.

Summary
This study investigated which factors best predict death and amputation in patients with necrotizing soft tissue infections (NSTIs) of the upper extremity, a rapidly progressing and life-threatening condition that destroys tissue and causes widespread organ dysfunction. Researchers retrospectively analyzed data from 99 patients treated at a single tertiary care center, calculating established clinical severity scores—the LRINEC and qSOFA—alongside patient characteristics and surgical details to identify meaningful predictors of outcomes. Among the cohort, 12 patients died in the hospital and 7 underwent amputation, with the strongest independent predictor of death being vasopressor dependency outside of surgical anesthesia, indicating that patients requiring blood pressure support beyond the operating room were at the greatest risk. Notably, the LRINEC score, a widely used tool for diagnosing necrotizing fasciitis severity, did not effectively predict either death or amputation in this upper extremity population. These findings highlight the importance of early recognition, aggressive resuscitation, and prompt surgical debridement in managing upper extremity NSTIs, while also suggesting that current scoring systems may have limited utility for guiding prognosis in this specific patient group.

Publication Date
2022-05-10

Faculty
Stephen Kennedy, MD

Description
Ring avulsion injuries are an uncommon, often catastrophic, pattern of digit injuries that result from sudden traction onto a ring-bearing digit. The reconstructive treatment of these injuries can be complex because of the characteristic involvement of nerves, muscles, vasculature, and bone. There is paucity of literature describing isolated arterial injuries in the absence of overlying soft tissue and underlying bone involvement. We present an unusual case of a closed ring avulsion injury,...

Publication Date
2022-04-13

Faculty
Yusha Katie Liu, MD

Description
Objective Recently, authors have investigated using the proximal hamate as osteochondral autograft for proximal pole scaphoid reconstruction in the case of nonunion with avascular necrosis. The aim of our study was to analyze the morphology and anatomic fit of the proximal hamate compared with the proximal pole of the scaphoid using cadaveric specimens. Materials and Methods Ten cadaver specimens (five males and five females) were dissected. Scaphoid and proximal hamate bones were measured by...

Publication Date
2021-06-10

Faculty
Jerry Huang, MD

Description
CONCLUSIONS: These cases highlight a rare but severe complication of dorsal hand/wrist infection. Early surgical intervention should be considered to prevent this complication, which may have permanent functional consequences and requires complex reconstructive and rehabilitative efforts.

Publication Date
2021-03-03

Faculty
Nicholas Iannuzzi, MD